ION-100 / ION-100T (CORNERSTONE Series)

Single Channel Iontophoresis Generator


The ION-100(T) uses an extremely accurate constant current source operational amplifier with +130 compliance voltage. The current output range is selectable between +/- 200nA and +/- 2000nA.

The front panel is arranged to facilitate easy operation. The POSITIVE, NEGATIVE current controls and the eject polarity controls operate as a team to determine both the magnitude and the polarity of the passing and the holding currents passed by the drug containing electrode.

To eject a cationic drug (positively charged) it is necessary to pass a positive current, to then prevent diffusion of that same cationic drug a negative "backing" or retaining current is required. The converse is true for anionic drug, negative for eject and positive for retain.

A "no" current flow situation can be obtained ether by setting both POSITIVE & NEGATIVE controls to 0nA on the dial or by placing the EJECT POSITIVE/NEGATIVE toggle switch to OFF/EXT.

The EJECT/RETAIN switch provides a manual control over the time period of drug injection. In the EJECT position the preprogrammed EJECT current passes drug through the micropipette barrel. The RETAIN position supplies the preprogrammed RETAIN current to hold the drug in the micropipette barrel.

If other than manual time control is desired, the EJECT/RETAIN switch should be placed in the AUTO or GATE position. In this position, the timing can be controlled by ether the EJECT TIMER (ION-100T only) or by the GATE input BNC on the back panel.

The GROUND push button switch shorts (grounds) out the current generator and micropipette barrel.

External analog current programming is accomplished by injecting +10 volt to -10 volt programming voltage into the back panel EXT COMD BNC.

SUM Channel:

When using 2 or more ION-100(T)'s together one can be configured as a SUM channel. The SUM channel output supplies a current equal in magnitude but opposite in sign to the algebraic sum of the currents from the sum outs of the other ION-100(T) in the SUM chain. To configure several ION-100(T)'s together with one as a SUM channel the SUM OUT of the first unit is plugged into the SUM IN of the second unit and so on until the last unit to be used as the SUM channel has the SUM out of the previous unit is plugged into the EXT COMD input of the SUM channel.



Current Source Parameters

Compliance voltage

260 V peak to peak

Maximum current


Maximum electrode resistance

See Table.

Maximum Electrode Resistance




650 Meg Ohm


65 Meg Ohm

Current Programming

Front panel

Positive and Negative 200nA/2000nA one-turn controls. Scaled by Range switch.


200 nA/Volt, rear panel BNC. Maximum input 10 volts (2000nA Command).


Current Monitor +/-1999 nA.

Cabinet Size

2.7" high, 7.5" wide, 9.7" deep.

Power (PS-100)

115 or 230 VAC (selectable with internal switch), 50/60 Hz, 35 W.



Single Channel Iontophoresis Current Generator +/-130volt compliance



Single Channel Iontophoresis Current Generator w/ timer functions +/-130volt compliance



130 volt Power Supply (operates up to 5 units)


HS-BNC Passive "Pencil" BNC probe 5 feet long (mates with HB-180 holder)
HB-180 Universal Pipette Holder for use with 1.0 to 1.8 millimeter glass
See Holders

Download the Manual (PDF)

Warning: This equipment is not intended for use in human applications or human experimentation.

[ Home | News | Products | Ordering | Feedback ]

Dagan Corporation Minneapolis MN USA  Email: 12/10