BVC-700A Whole Cell Clamp (CORNERSTONE Series)

Bridge & Voltage Clamp Amplifier

"The ideal cost effective amplifier for ultra high speed Patch Pipette Current Clamping" 

Press HERE to view full size front panel

Features:

  • Operates as both a Bridge Current Clamp and a Continuous Voltage Clamp Amplifier. 
  • Small Box Probe in five current ranges with automatic decimal point selector on meter
  •  
  • Gated Independent Step Command current or voltage generator with a three digit digital push wheel programming dial.
  •  
  • LED indicator lights for headstage multiplier and meter mode
  •  
  • Buzz control to facilitate cell penetration
  •  
  • Small size takes up less rack space, yet is uncluttered, easy to use, with well defined controls
  •  
  • Optional 1000 Gain AC Coupled Headstage for extracellular recording 

2 New Features for the BVC-700A:

The BVC-700A is a microelectrode preamplifier with both Bridge Current Clamp and Continuous Voltage Clamp Capability. The BVC-700A was designed to serve a wide variety of applications including: Continuous Voltage or Current Clamping; Patch pipette recording; Intracellular recording; Extracellular recording (with the optional 8024 headstage). 

The BVC-700A is a complete instrument with DC and pulsed voltage clamping and current passing capability, filtering, electrode impedance testing, and a LCD voltage, current, and electrode impedance meter . The optional BUZ-1 Universal Buzz Box adds amplitude, duration, and frequency features for rupturing into cells (buzzing). 

 

    Specifications

    • Headstage size: 3.7 cm (1-1/2") X 2.9 cm (1-1/8") X 2.3 cm (7/8")
    • Standard Headstage: N=.1 (although the N=.1 is the standard Headstage, the N=.01 is also a very popular headstage for patch pipette current clamping)

     Current Multiplier N

    Max I

    RF (Feedback resistor )

    RMS Noise / Bandwidth / Model cell Resistance

    Bridge Balance Range (ohms)

    Cp range

    Input Resistance

    10

    10uA

    1Meg

    25uV,10Khz,1M

    100K&1M

    20pF

    10Gig

    1

    1uA

    10Meg

    50uV,10KHz,10M

    1M&10M

    20pF

    100Gig

    .1 (standard)

    100nA

    100Meg

    50uV,1KHz,100M

    10M&100M

    20pF

    1000 Gig

    .01

    10nA

    1Gig

    40uV,100Hz,1G

    100M&1G

    20pF

    10KGig

    .001

    1nA

    10Gig

    35uV,10Hz,10G

    1G&10G

    20pF

    100KGig

  • Filter Response: Switch selectable DC to 1kHz, 3kHz, 5kHz, 10kHz, 30kHz and Wide Band 
  • Input Bias Current: 1 x 10-12 Amps (Adjustable to zero) 
  • Rise Time to Pulse: Typically 10 microseconds into 10 megohm resistor (10 to 90%), 50 microsecond into 100 megohm.
  • Voltage Gain: X10 and X100 
  • Output Impedance: 500 ohms all outputs 
  • Offset Voltage: +200mV 
  • Balance Reading: Two ranges 0 to 1 megohm and 0 to 10 megohm divided by headstage scaling N (10 turn digital dial) 
  • Electrode Impedance Test: 1mV per megohm square wave (N), Also reads on meter.
  • Holding Current Range: 0 to +100 nA (10 turn digital dial) scaled by headstage multiplier N 
  • Holding Voltage Range: 0 to +200 mV (10 turn digital dial) 
  • Step Command Range V Camp: Two ranges +99.9mV(X0.1), +999mV(X1) 
  • Step Command Range I Camp: Two ranges +99.9nA(X0.1), +999nA(X1) scaled by headstage multiplier N 
  • Gated Input: +2 volt to +20 volt level turns on programmed Step Command 
  • Monitor: 1999 mv meter displays voltage, current and electrode impedance (decimal point is automatically set) 
  • External Command Input BNC: V Clamp- 20mV/V; I Clamp: Selectable 20nA/V or 100nA/V scaled by the headstage multiplier
  • Size: 3 1/2 inch by 19 inch rack 
  • Power: 115/230VAC 50/60Hz 
  • Electrode Holders: Low noise polycarbonate in two sizes: HB120 for glass 1.0 to 1.2mm O.D.; HB180 for glass 1.5 to 1.8 mm O.D. (order separately). 
  • Extracellular Recording: 8024-15 Extracellular Headstage (AC coupled, voltage gain = 1000) (order separately). 
  • Optional: 7001 Spare Headstage (Specify N) 

 APPLICATION EXAMPLE  To view an application example showing the improved results obtained when a temperature controller is used in conjunction with a voltage clamp experiment, click here. 

BVC-700A

Intracellular Bridge & Voltage Clamp Amplifier with one headstage (standard is N=0.1) Also requires the use of one Pipette Holder (please see below )

$5,420.00 

HB120

Pipette Holder for use with 1.0 to 1.2 millimeter glass (Also see Pipette Holders and Parts section 

$ 75.00 

HB180

Universal Pipette Holder for use with 1.0 to 1.8 millimeter glass (Also see Pipette Holders and Parts section) 

$ 85.00 

7001

Spare Headstage (Specify N=.001, .01, .1, 1, 10 )

$ 420.00 

8024-15

Extracellular Headstage (AC coupled, voltage gain = 1000) 

$ 550.00 

8024-7001
Dual Mode Extracellular & Intracellular Headstage (for IX1, IX2-700,BVC-700)(Specifiy N = 1 or 0.1) $1,090

BUZ-1

Universal Buzz Box (see BUZ-1 data sheet page for details) 

 $ 490.00 

 

 Other Intracellular Preamplifiers: 

Other Patch Clamps: 

    • 3900A (high performance integrating, extremely fast current clamp) 
    • PC ONE (general purpose, moderate cost) 

Warning: This equipment is not intended for use in human applications or human experimentation.

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Dagan Corporation Minneapolis MN USA ) Email info@dagan.com 8/9