2400A Extracellular Preamplifier Current Pump System
"A superb low noise preamplifier"
|The model 2400A PREAMPLIFIER-CURRENT PUMP system is designed to be the most versatile, capacitively neutralized preamplifier available. In addition, low noise, the built-in audio monitor amplifier and the ability to inject current and voltage through the microelectrode by several different methods will make the 2400A virtually the most trusted and capable instrument in your laboratory.||Dagan has combined its knowledge of biological recording amplifiers and current injection techniques to produce a truly versatile instrument, the standard of accuracy. The power, flexibility and ease of operation are unequaled in the industry. The, 2400A is also the perfect recording preamplifier companion to the Dagan model 6400Advanced Programmable Six Channel Micro-Iontophoresis Current Generator. Together they provide you with the most sophisticated and accurate instrumentation available for doing micro-iontophoretic drug injection.|
The heart of the 2400A system is its versatile preamplifier section made up of high gain, low noise neutralized preamplifier, active filters, and an audio amplifier. The neutralized input capacitance allows fast rise time signals to be viewed with high microelectrode resistance's.
Since extracellular and micro-iontophoretic recording can involve microelectrode resistance's into the tens of megohms, current noise (in addition to voltage noise) becomes an important consideration. The 2400A system preamplifier was designed to be used with both high and low impedance electrodes. In all situations it will provide noise levels close to the Johnson noise theoretical minimum (produced by the microelectrode resistance).
The voltage gain of the preamplifier section is very high (switch selection of: 50, 100, 200, 500, 1000, 2000, 5000, or 10,000). No other additional amplification should ever be needed between the microelectrode and the recording instrumentation.
A CALIBRATE switch allows a precise signal to be passed form the preamplifier to calibrate recording or viewing instrumentation
A full complement of active filters means that frequency response can be tailored to provide maximum signal to noise ratio. The seven frequencies for both the high and low frequency cutoff filters were chose to provide for a complete range of recording bandwidths. Selection is made by convenient, fast action, push button switches.
By switching on the twin-tee active LINE NOTCH FILTER, interference problems caused by 60 (or 50) hertz power lines are eliminated.
The internal audio power amplifier fulfills the requirement for audio monitoring of the preamplifier output. The audio level is determined by the MONITOR control and a separate 8 ohm speaker (available as an option) plugs into the instrument back panel to provide sound where you want it.
Your microelectrode recording site can be marked for easy visual identification by using either the STAIN switch or the controlled but smaller currents from the CURRENT PUMP.
The STAIN generator provides a high level resistive limited current with polarity selections for use with both metal and glass electrodes. The 2400A also provides for any future stain requirements vow may have by giving you direct access to the electrode via the EXTERNAL BNC connector.
An ultra low noise experimental setup the absence of capacitive loading effects are made possible by the use of a probe headstage containing the first preamplifier gain block and also all circuitry needed for the other microelectrode termination's.
Capacitive neutralization is at your fingertips with a high resolution neutralization control located on the probe. This feature gives you the capability to fine tune signal rise times when your miroelectrode resistance's are greater than a few megohms.
A low noise shielded probe cable is so flexible that the lightweight probe head stage will always stay where you want it.
HEADSTAGE ELECTRODE CONTROL SWITCH
The ELECTRODE control switches provide a unique combination of microelectrode termination's. A push of the button changes the 2400A system from(1) a high current stain generator for marking recording site to a, (2) controlled positive or negative ideal current source up to 1000nA to (3) a low noise neutralized preamplifier and an audio monitor, or (4) gives you a direct connection to your microelectrode for any future need that you may encounter. All this without ever touching the probe or the microelectrode.
The CURRENT PUMP provides a precisely regulated Current from 0 to plus or minus 1000 nA for injection of dyes or drugs from the microelectrode by iontophoresis. The currents can be injected through the probe into the microelectrode by pushing the ELECTRODE switch to the CURRENT PUMP position. If the need should arise for the CURRENT PUMP to be terminated in an electrode other than the recording electrode, its output current is always available at the AUX PUMP OUT BNC connector. With the PUMP LEVEL switch set to the INTERNAL position, the current magnitude is set by the ten-turn digital readout dial. the polarity is set by the PUMP POLARITY switch. The OFF position of this switch programs the ideal current generator to zero nA output, this is a quick means of going form the dialed CURRENT PUMP level to zero nA.
Supplying an external bipolar analog signal into the EXT REF BNC jack with the PUMP LEVEL switch set to EXTERNAL allows the ideal current source to be programmed externally by the magnitude and polarity of the reference signal. (Interfaces directly with the D/A converter on any computer.
PROBE INPUT CONNECTORS (please specify one of the two below)
The 2400A comes with BNC connector, or 1mm Tip Jacks
BNC (the most requested and is standard if nothing else is specified)
Mates with Dagan HB180 microelectrode holders for glass pipettes.
1 mm Tip Jacks
Mates with standard 0.04 inch Tip Jack connector
|2400A||2400A and 2410A Capacitance Compensation Probe and input connectors. Now standard with Resistance Test (Z) Gain Control (I) and Pulse Test (T). (Please Specify Input Connector above)||$3,250.00|
|D||DC/Battery Operation input jacks.||$ 95.00|
|2410A||Spare probe for the 2400A System. (DB-9 connector)||$ 770.00|
|2410||Spare probe for the 2400 System. (Amp-9 connector)||$ 770.00|
|2430A||Differential probe for the 2400A System (DB-9 connector)
Only comes with Tip Jack connectors
Download the Manual (PDF)
|See the Holders and Accesories section for mating connectors, jacks and cables|
Warning: This equipment is not intended for use in human applications or human experimentation.
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Dagan Corporation Minneapolis MN USA Email: firstname.lastname@example.org 03/14